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Six young men and six young women were participated in this study. Muscle sample was obtained from vastus lateralis muscle. To examine potential gender differences within each fiber contractile properties CSA, maximal isometric force, SF, maximal shortening velocity and relationship between CSA and SF of single fiber using Pearson correlation. After mechanical measurements, single muscle fiber determined MHC isoforms using silver stain.
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Sex-Based Differences in Skeletal Muscle Kinetics and Fiber-Type Composition

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Sex Differences and Mechanisms of Task-Specific Muscle Fatigue

Women can be less fatigable than men due to sex-related differences within the neuromuscular system that impact physiological adjustments during a fatiguing task. The involved mechanism s for the sex difference, however, is task specific. This review explores the novel hypothesis that variation of the task will alter the magnitude of the sex-difference in muscle fatigue and the contribution of involved mechanisms. Muscle fatigue is classically defined as an exercise-induced decline in maximal voluntary muscle force or power 5. It develops in men and women soon after the onset of sustained physical activity and is often quantified as a reduction in maximal voluntary contraction MVC force after or during maximal and submaximal exercise 5. Muscle fatigue can occur despite continued and successful performance of a submaximal task.
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Sex Differences and Mechanisms of Task-Specific Muscle Fatigue

Previous studies have identified over 3, genes that are differentially expressed in male and female skeletal muscle. Here, we review the sex-based differences in skeletal muscle fiber composition, myosin heavy chain expression, contractile function, and the regulation of these physiological differences by thyroid hormone, estrogen, and testosterone. The findings presented lay the basis for the continued work needed to fully understand the skeletal muscle differences between males and females.
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Sex differences in human physiology are distinctions of physiological characteristics associated with either male or female humans. These can be of several types, including direct and indirect. Direct being the direct result of differences prescribed by the Y-chromosome, and indirect being a characteristic influenced indirectly e. Sexual dimorphism is a term for the phenotypic difference between males and females of the same species.

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